In Moscow, where Navalny's allies want to protest on a square by the Kremlin where Putin is set to address the two chambers of parliament earlier on Wednesday, the mayor's office said the protest would not be authorized because of the COVID-19 outbreak.
"In some countries, they have developed a highly unseemly habit of picking on Russian Federation for any reason, and most often for no reason at all - a kind of sport", said Putin, standing alone on a vast stage flanked by white, blue and red national flags and a backdrop of a giant double-headed eagle.
Russian cities are seeing unauthorized rallies in support of jailed opposition figure Alexey Navalny. Navalny's team has said protests will be held in more than 100 cities and towns.
They called on Russian authorities to allow Navalny "to be evacuated for urgent medical treatment overseas", stressing that "the Russian government is accountable for Mr Navalny's life and health while he is in detention".
Elsewhere in Russian Federation, police detained some 50 people in the city of Ufa.
In an apparent reference to the USA and its allies, the Russian leader denounced those who impose "unlawful, politically motivated economic sanctions and crude attempts to enforce its will on others".More news: Ontario records 3,469 new COVID-19 cases, 22 deaths
Russian President Vladimir Putin delivered his annual State of the Union address on Wednesday (21 April), presenting a narrative according to which the West was playing a risky and hostile game against his country, which had no other choice but to defend itself. Lyubov Sobol, one of the faces of Navalny's popular YouTube channel, and Kira Yarmysh, his spokeswoman, were both detained in Moscow. She was taken to a police station and charged with organising an illegal gathering.
Sobol was removed from a taxi by uniformed police, said her lawyer, Vladimir Voronin.
Police conducted raids at Navalny's regional offices in the cities of Krasnodar and Kurgan, according to OVD-Info, which monitors protests and activist detentions.
In St. Petersburg, the State University of Aerospace Instrumentation posted a notice warning that students participating in unauthorized demonstrations could be expelled.
Pointing to previous rulings by the European Court of Human Rights, the experts stressed that "there is no valid legal basis for Mr Navalny's arrest, trial and imprisonment in Pokrov". Russian officials have rejected the accusation.
Navalny, who is on hunger strike in a Russian penal colony, has been incarcerated under harsh conditions without adequate medical care and has been barred from seeing doctors of his own choosing, they said.More news: Walter Mondale, Former Vice President and Failed Presidential Candidate, Dies at 93
Navalny, who survived a nerve agent poisoning last year that Russian Federation denies carrying out, was sentenced in February to 2-1/2 years for parole violations related to an embezzlement case that he says was politically motivated.
Russia's penitentiary service insists that Navalny was getting all the medical help he needs.
Navalny's physician, Dr. Yaroslav Ashikhmin, said recently that test results he received from Navalny's family showed sharply elevated levels of potassium, which can bring on cardiac arrest, and heightened creatinine levels that indicate impaired kidneys and mean that he "could die at any moment".
On Sunday, he was transferred to a hospital in another prison and given a glucose drip.
Putin backed claims by Belarusian President Alexander Lukashenko that his security services had thwarted an alleged USA plot to assassinate him, suggesting senior United States officials were involved in a "coup attempt" and accusing the West of pretending "that nothing is happening".
"It is, of course, an element of escalation", Ashurkov told the AP. I'm confident that now, too, we will find ways to work.More news: Signs discouraging travel into B.C. to be posted along Alberta border