Officer Genae Cook of the Indianapolis Metropolitan Police Department told reporters Friday morning that there were "multiple people with injuries consistent with gunshot wounds" as a result of the shooting.
The shooter wasn't immediately identified, and investigators were in the process of conducting interviews and gathering information.
Family members gathered at a local hotel to await word on loved ones.More news: India reports record 200,000 new covid-19 cases as outbreak spreads
Flights from the nearby worldwide airport, where the FedEx Express cargo airline has a hub, are not affected.
FedEx said in a statement early Friday that it was cooperating with authorities and working to get more information.
A FedEx spokesperson said the company was aware of the shooting at its ground facility near the airport.
Footage from the scene shows police tape in the auto park outside and multiple emergency service vehicles.More news: Taliban Shun Afghanistan Talks Until Foreign Forces Go
At first Jeremiah Miller and Timothy Boillat thought the sound was from a auto, but after hearing more, Miller stood up and saw a man with a weapon, he told the station. "I immediately ducked down and got scared and my friend's mother, she came in and told us to get inside the auto".
WASHINGTON, April 16 ― Multiple people were shot in an incident today in the U.S. city of Indianapolis, according to police, although the severity of the victims' injuries was not immediately clear. Five people, including a pregnant woman, were shot and killed in January, and a man was accused of killing three adults and a child before abducting his daughter during at argument at a home in March. Authorities said there was no further threat to public safety.
Another witness told WTTV that his niece was sitting in her vehicle in the driver's seat when the gunfire erupted, and she was wounded.
Indianapolis State Police Sgt John Perrine said Interstate 70 near the facility was closed in both directions. As officers arrived, they came upon an active shooter, she said.More news: Biden tells Putin to ease tensions on Ukrainian border, proposes summit
Some said employees aren't allowed to have their phones with them while working shifts at the facility, making it hard to contact them, WTHR-TV reported.