"Some members of the royal family have been trying to instrumentalise Jordan's economic and governance problems to present themselves as reformists who possess the solution to Jordan's challenges", said Ms Khatib.
In a video the BBC said it obtained from his lawyer, Prince Hamzah said a number of his friends had been arrested, his security removed and his internet and phone lines cut.
State-run news agency Petra says among those arrested for "security reasons" were former close aide to royal family Bassem Awadallah.
Special Assistant to the Prime Minister of the Middle East Tahir Ashrafi has expressed Islamabad's solidarity with Jordanian authorities, following an alleged plot to destabilise the country.
The alleged plot "included at least one other Jordanian royal as well as tribal leaders and members of the country's security establishment", the U.S. daily added.
On Saturday, The Washington Post reported that several royal and palace officials were arrested in Amman over allegedly plotting to overthrow the king.More news: USA ousts Astra from factory, puts J&J in charge
He denied being part of "any conspiracy or nefarious organization", but charged that the Hashemite kingdom had "become stymied in corruption, in nepotism, and in misrule".
"The kingdom affirms its full support, with all its capabilities, to all decisions and measures taken by King Abdullah and His Highness Prince Al Hussein bin Abdullah II, the Crown Prince, to maintain security and stability", the Saudi royal court said in a statement.
Foreign minister and deputy PM Ayman Safadi said Jordanian intelligence had intercepted certain communications at what he called the "zero hour".
Stability in Jordan and the status of the king has always been a matter of concern, particularly during the Trump administration, which gave unprecedented support to Israel and sought to isolate the Palestinians, including by slashing funding for Palestinian refugees.
Reuters quoted Safadi as saying that Hamzah had liaised with foreign powers and been under investigation for some time.
"This sedition was nipped in the bud", Safadi said.More news: Dutch stop giving AstraZeneca vaccine to under-60s pending review
On Sunday, in the wake of the security sweep, she tweeted that she was "praying that truth and justice will prevail for all the innocent victims of this wicked slander".
He is seen as religious and modest, in touch with the common people and similar to his beloved father, the late King Hussein.
"What Prince Hamzah said is repeatedly heard in the homes of every Jordanian", said Ahmad Hasan al Zoubi, a prominent Jordanian columnist.
According to the same source, "there is certainly resentment on his part, because he has never digested losing his title of crown prince".
Jordan's Joint Chiefs of Staff head Major General Yousef Huneiti said Hamzah had not been detained, but "asked to stop some activities that could be used to shake the stability and security of Jordan".
Majali told Roya "No one will be more compassionate to Prince Hamzah than his big brother His Majesty King Abdullah II".More news: Fully vaccinated people can fly in US
Jordan, whose royal family traces its lineage back to Prophet Muhammad, has been ruled since 1999 by 59-year-old Abdullah II, the oldest son of the revered late King Hussein and his second wife, the British-born Princess Muna.