Pfizer Inc said on Friday it had finished enrolling children aged between 12 and 15 in a study testing its COVID-19 vaccine, as the US drugmaker seeks to expand the shot's use among different age groups.
In most cases, the recommended dosing interval of three weeks for Pfizer Inc's vaccine and four weeks for Moderna Inc's vaccine should be followed, the U.S. Centers for Disease Control and Prevention (CDC) said in its guidance on Thursday.
A heavily female ratio was also noted with the Pfizer vaccine, which experts say could be due to the fact that more women than men have been vaccinated, at a rate of approximately two to one.
Moderna's COVID-19 vaccine is one of two that have been authorized for emergency use to fight the pandemic across the US. In fact, they already have. The first report on US cases of anaphylaxis following administration of the Pfizer vaccine suggested it occurred at a rate of 11.1 cases per million doses given.More news: Austin confirmed as first Black defense secretary
Gavi chief executive Seth Berkley said almost 150 million doses of the AstraZeneca-Oxford vaccine were ready to ship through Covax - pending emergency use approval from the World Health Organization, which is on course to happen in mid-February.
In Friday's report, six of the 10 people who developed anaphylaxis were hospitalized and four of them needed to be intubated to assist their breathing. To date there have been no reports of fatal cases of anaphylaxis associated with Covid vaccines in the United States.
All 10 of the people who developed anaphylaxis were given epinephrine, the drug in EpiPens that is used to combat severe allergic reactions.
Vaccination sites must be equipped and able to treat severe allergic reaction, and able to transport patients to the hospital if necessary, the CDC said.More news: The Real Meaning Behind Sabrina Carpenter's New Song Skin
Anaphylaxis occurred quickly in the people affected, with the median time to the start of symptoms being 7.5 minutes.
Covax aims to secure enough Covid-19 vaccines this year for the most vulnerable 20 per cent in every country, rich or poor.
"It's important that anybody who has had anaphylaxis talk to their vaccinator about that, and make sure that if they choose to be vaccinated, they wait the 30 minutes", Dr. Thomas Clark, who's been tracking allergic reactions after vaccination at the CDC, told reporters earlier this month.More news: Cold with a chance of snow: Northeast Ohio’s weekend weather forecast