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AstraZeneca to hold more vaccine trials

  • by Valerie Santiago
  • in Medical
  • — Nov 29, 2020
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The Health Ministry (MoH), through the National Pharmaceutical Regulatory Agency (NPRA), will ensure that the Covid-19 vaccine approved to be registered and marketed in Malaysia is safe, of good quality and has optimum efficacy according to requirements set by the World Health Organisation (WHO).

"This letter is an important step towards deploying a vaccine as quickly as safely possible".

American Airlines Group Inc. said it has been conducting trial flights from Miami to South America to test the thermal packaging and operational processes for shipping vaccines.

But media in the United States and Europe say the volunteers in the group with an efficacy of 90 percent were mistakenly given a half initial dose of the vaccine.

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The organization had already claimed that 90% efficacy in one dosing scheme was shown by the vaccine that was produced at the University of Oxford, when a half-dose was given, followed by one full dose at least a month later, and 62% efficacy in two full doses at least one month apart. Encouraging results from the phase III trials of the Oxford University/AstraZeneca were also published this week. "It is the opposite of what is needed in our view".

"Whenever you've got a trial that the company wasn't entirely truthful with what happened in the beginning, that sets people's confidence back", Gardam said on CBC News Network on Thursday. "The real problem here is people are really on edge and any little tweak that happens, people worry about it and rightly so".

Earlier in the day, British Prime Minister Boris Johnson named Nadhim Zahawi, now a junior business minister, as the minister responsible for the deployment of COVID-19 vaccines.

"And secondly, it needs to be reviewed in terms of the data and questions that may come up during the review".

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The question that immediately arose was: why such a wide variation in the effectiveness of the vaccine at different doses?

The P600-million agreement calls for the delivery of 2.6 million doses of the AZD1222 vaccine to 1.5 million Filipinos between May and June 2021.

"I won't tell you we expected the efficacy to be higher", Soriot told Bloomberg.

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