That includes 59 patients struggling in intensive care or critical care.
Active cases of the virus also reached a new high of 7,732 in the province, surpassing Monday's record for active cases by almost 400 cases.
There have been 10 new COVID-19 related deaths, for a total of 358 deaths in British Columbia.
"As we have seen, this virus doesn't pause when we are exhausted and doesn't wait for us to catch up", said Provincial Health Officer Doctor Bonnie Henry.
"As we have seen, this virus doesn't pause when we are exhausted and doesn't wait for us to catch up".More news: Taylor Swift 'Folklore' Concert Film to Debut on Disney Plus
"We need to do more", she said.
10,200 people are under active public health monitoring as a result of an exposure.
She also announced six more outbreaks in B.C.'s health-care facilities, at North Peace Senior Housing, Queens Park Care Centre, CareLife Fleetwood, Sunset Manor, Renfrew Care Centre and Lions Gate Hospital.
Interior Health says there are now 302 active cases in isolation, with two people in hospital (none in ICU).
"Over the next two weeks, we need to urgently reduce the level of transmission in our province to keep our schools and workplaces open and relieve the very real stress we are seeing right now on our healthcare system", Dr. Henry said.More news: San Diego County reports record 1,546 new COVID-19 cases
The health authority also announced five deaths due to the virus. "We've learned as we moved into winter, that the virus spreads more easily".
Approximately 19,605 people who have tested positive for COVID-19 in B.C. have recovered.
She said social gatherings and events are necessary sacrifices residents must make to protect those parts of the economy. The health agency says anyone who visited The Morrissey at 1227 Granville Street on either November 12 or 13, between 6 p.m.to 11 p.m. on both days, may have been exposed to the virus and should monitor themselves for symptoms of COVID-19.
"It's important that we continue to look after our mental health and our physical health", Henry said.More news: AstraZeneca Says COVID-19 Vaccine 70% Effective