The Blues are in good form going into the game at St. James' Park on Saturday but are set to be without a few key players due to injuries and illness.
A 12:30 GMT start on Saturday is distinctly unhelpful, Lampard believes, at a time when he feels the Premier League should be doing all it possibly can to guide clubs through the hard pandemic period.
Lampard has yet to see several players returning from global duty and with the shortest recovery time possible before travelling to the north-east for the first Premier League game of the weekend.
"We are still waiting for some of the results of the tests that we now have to do as players are back from internationals. We have to continue to look at the best way to change it", Lampard said.More news: 'World's only white giraffe' gets Global Positioning System tracker
'Unfortunately some players are arriving back this afternoon, so with the 12.30pm kick off it brings a lot of challenges'.
"It's not the best". When you look at the scheduling it is a common sense factor. I don't want to make more of it than it is, because we want as many games out of Christian as we can possibly get because of his ability.
"If you look over the course of the season, at global duty, it is absolutely not the optimum way to have players preparing for a Premier League game, which is an incredible brand all around the world so you want the best of the brand".
"You want the best of the brand and it's very hard for us to prepare for this game anywhere near where we are preparing to our best. But we have a great medical team here and we are very much joined up on the idea of getting the best of Christian by getting him fit as much as we can".More news: Twitter apologises in writing for showing Ladakh in China
Chelsea FC are looking to build on their fourth-placed finish in the Premier League from last season under Lampard. The numbers are there. There is a correlation of games, game after game after game.
"Thiago Silva has just landed and messaged me this afternoon so he probably won't be going to Newcastle because of the length of his journey and timings".
"We need to try to find the right balance between playing and resting and maintenance during the week to try to get the best out of him".More news: Ontario to get 2.4 million COVID-19 vaccines in early 2021: Elliott