Poorly resourced hospitals across Africa, which is nearing a million cases of COVID-19 - more than half of them in South Africa - have struggled to cope with a burgeoning case load amid a global scramble favouring richer nations in procuring ventilators and protective gear.
He said of the 503 290 infections, 342 461 patients have recovered from the disease, increasing the recovery rate in the last 24 hours from 66 to 68 percent.
South Africa is the hardest-hit country on the continent and accounts for half of all reported infections in Africa.
Slightly more than three million people have so far been tested for the virus in South Africa, which confirmed its first case five months ago, and 8,153 deaths have been recorded.
Of the cumulative total of 503 290 cases, 342 461 people have recovered and 152 676 cases were now active.More news: Vietnam reports 40 more Covid-19 cases, total rises to 586
This brings the total to 503,290 - the fifth-highest worldwide, behind the US, Brazil, India and Russian Federation, according to Johns Hopkins University in the US.
Over 17.8 million COVID-19 cases have been reported worldwide, with recoveries exceeding 10.5 million, according to figures compiled by the US' Johns Hopkins University.
The global coronavirus pandemic is the most serious public health crisis that the world has faced in over a century. We deeply mourn this loss and offer our sympathies to the families and friends who are in grief.
South Africa's Gauteng province - which includes Johannesburg, the country's largest city, and Pretoria, the capital - is the country's epicenter with more than 35% of its confirmed cases. While it may be too soon to draw firm conclusions, this suggests that the prevention measures that South Africans have implemented are having an effect.More news: Thousands march in Germany against Covid curbs
The national lockdown succeeded in delaying the spread of the virus by more than two months, preventing a sudden and uncontrolled increase in infections in late March.
Our recovery rate is now around 68%.
Ramaphosa has warned that now, more than ever, South Africa's persistent problem with widespread graft is endangering people's lives. On Thursday, the top health official in Gauteng province was forced to step down over corruption allegations related to government contracts for COVID-19 personal protective equipment.
Each CPAP device consists of some 30 separately manufactured components, he said, adding that final assembly now takes place at the Cape Town factory of medical supplies firm Akacia Medical ahead of distribution to hospitals across the country. Several public hospitals in the Eastern Cape were overwhelmed as infections rose in the province, and a specialist team has been deployed to address this challenge.
But Mr Chopera said provinces such as Eastern Cape and KwaZulu-Natal could fare badly with a big increase in cases, as their health systems are less prepared. We need, however, to continue with these efforts to further increase the capacity of our health facilities.More news: Umbrella Academy Season 2 Opening Scene Has Soviets Invading US
He said in August that the National Ventilator Project would deliver 20 000 locally produced, non-invasive ventilators to where they were most needed. A dedicated team drawn from several institutions, led by the Biovac Institute, is preparing to manufacture doses of a successful vaccine locally.