But asked about polling that said around a third of Americans would not get a coronavirus vaccine when one is developed, Dr Fauci said that such a high level of refusal would mean it was "unlikely" the vaccine would get the USA to herd immunity level.
He added later, however, that pushback to getting a vaccine - some polls say as many as one-third of Americans would refuse to be vaccinated - could result in a lack of herd immunity.
Fauci was asked if herd immunity could be achieved through two-thirds of the population taking a vaccine that was only 70% to 75% effective.More news: Kyrgios brands Boris Becker a 'doughnut'
Given the influence of anti-vaxxers, he added: "We have a lot of work to do" to educate people about the truth about vaccines. I would settle for [a] 70, 75 percent effective vaccine.
Fauci noted it will be hard to educate people about vaccines, because "there is a general anti-science, anti-authority, anti-vaccine feeling among some people in this country - an alarmingly large percentage of people, relatively speaking".
"Anyone who thinks it will be easy does not face reality".More news: European Union to decide to which 'safe countries' external borders will be opened
During an interview Saturday, the coronavirus task force member said many people took an "all or nothing" approach to distancing guidelines by either completely locking down or ignoring guidelines entirely. "It's going to be very hard".
"I can't make an accurate prediction, but it is going to be very disturbing, I will guarantee you that, because when you have an outbreak in one part of the country even though in other parts of the country they're doing well, they are vulnerable". "I'd hate to see CNN put out [a] wildly incorrect story", Michael Caputo said. Some are going to be A and some are going to be C somewhere, "he said, pointing out to NY that he did" really well.More news: New, free Windows 10 tool from Microsoft could prove to be invaluable
Responding to people's resistance to wearing masks, Fauci said it was "a recipe for disaster" and said some states had reopened too quickly. "So the standard classic paradigm of identification, isolation, contact tracing doesn't work no matter how good you are because you don't know who you're tracing".