How it works: The machine re-creates a level of pressure similar to that found inside the body, and pumps oxygen, blood, and nutrients to the livers while removing cell waste products like carbon dioxide.
Researchers say the next step is to use these organs for transplantation.
Scientists from University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich set out to improve the performance of their liver perfusion machine by having it closely replicate the function of the human body.
In addition the machine that perfuses the organs outside the body could be used to bring to life injured livers from cadavers after perfusing them for several days.More news: Greta Thunberg calls on Siemens to review Australia coal project
In keeping with the learn about, revealed within the magazine Nature Biotechnology, with the unconventional perfusion era, livers - or even injured ones - can also be stored alive out of doors the human frame for every week. The study was titled, "An integrated perfusion machine preserves injured human livers for one week".
The perfusion machine while in operation, with the liver within the white container at left.
Until now, livers could only be kept alive for up to 12 hours outside of the body.
"The success of this unique perfusion system - developed over a four-year period by a group of surgeons, biologists, and engineers - paves the way for many new applications in transplantation and cancer medicine helping patients with no liver grafts available", explained Prof.More news: Body Of Missing Ohio Teen Found In Chimney Of Unoccupied House
The research was published January 13 in the journal Nature Biotechnology. Pierre-Alain Clavien of the University Hospital Zurich (USZ). With the added time ex vivo, the scientists could fix the damaged livers, clearing them of fat deposits and facilitating tissue regeneration, for example. Now the donated as well as damaged livers could be preserved for a seven day period. With the added time ex vivo, the scientists would possibly perchance perchance per chance restore the broken livers, clearing them of fat deposits and facilitating tissue regeneration, as an illustration.
"The most important problem within the preliminary segment of our undertaking was once to discover a not unusual language that will permit verbal exchange between clinicians and engineers", mentioned researcher Philipp Rudolf von Rohr.
A liver connected to the perfusion machine. Alternatively, human livers may also be kept metabolically active for up to 24 hours by supplying oxygenated fluids and normothermic blood via a machine. If likely, this is able to perchance per chance double or per chance even triple the choice of livers readily available for transplant, in accordance to the paper. Lab tests were positive, showing normal function, robust cellular energy and intact liver structure.
"In the future, for patients with liver cancer, we may be able to take a section of the liver, grow it bigger and transplant it back into the patient".More news: SpaceX Crew Dragon ready for final key test before astronaut's launch