Wade Ormsby was a fugitive victor when he completed an impressive win from cable to cable in Fanling, closing with a 66 to finish in 17 low and four shots from Lowry, who signed with the low round of the last day.
Wade Ormsby carded four-under-par 66 for the third day in a row to complete a wire-to-wire win.
Ormsby birdied 11 but dropped another shot on 15 before another birdie on 17 effectively confirmed his wire-to-wire victory as he closed with a winning total of 17-under-par.
Seeing his countrymen and women "pulling together" to fight the blazes that have scorched an area the size of Ireland had given him motivation to perform on the world stage, he said.More news: Scientists say seven billion year-old stardust is oldest solid material found
The Portrush golfer has shot a final round of 64 at the par 70 course to finish the tournament in a three-way tie for fourth on nine under.
"I am right where I want to be, and I am looking forward to the weekend", Lowry said after a round that included five birdies. We started off not bad, the weather was fine but the wind got stronger and stronger.
"I'm very happy with myself, but fair play to Wade, he's run away with it and didn't really give us a chance", claimed theIrishman "But I headed out there as well as did as long as I could".
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Lowry surmounted a late charge by storming up the leaderboard with a 64, having started the day six shots back of Ormsby in a share of ninth place.
The 39-year-old, who led after the first round and never relinquished his advantage, won the Hong Kong Open in 2017.
Three other players from the city made the weekend cut - a record that has brought cheer to Hong Kong's sporting community after months of unrest saw several prominent events cancelled.
Other sporting events, such as October's Hong Kong Open tennis and the city's worldwide squash championship in November, were cancelled due to fears over the impact protests could have on the tournaments.More news: EU Launches Iran Nuclear Deal Dispute Action