"Alternatively, many small compounds in skin care merchandise that cause allergic touch dermatitis lack the chemical teams wanted for this response to happen", stated learn about co-leader Annemieke de Jong, Assistant Professor of dermatology at Columbia College Vagelos Faculty of Physicians and Surgeons in NY.
Researchers said the oil is not chemically manufactured so it is very popular but up to five percent of the population is allergic to it because it contains the small compounds which break down certain individuals immune systems, causing an allergic reaction. The researches have suggested that usually a few small chemicals are required to bind a lot larger protein for becoming visible to the T cells and a lot of the chemicals are able to do this as they undergo a reaction inside the body.
"However, many small compounds in skincare products that trigger allergic contact dermatitis lack the chemical groups needed for this reaction to occur", said study co-leader Annemieke de Jong, Assistant Professor of dermatology at Columbia University Vagelos College of Physicians and Surgeons in NY. Chemical compounds found in these products were thought to be too small and of the wrong chemical structure to be detected directly by T cells, which are the immune cells that set off ACD.More news: Aubameyang: I'm Arsenal captain and I love this club
According to a study published in Science Immunology, the chemical factor in skin products is a major factor in skin allergies, a chemical in consumer products used to displace natural fat-like molecules in skin cells called lipids.
A team of worldwide researchers from Monash University, Columbia University and Harvard Medical School has discovered how some compounds contained in cosmetic and perfume products can activate human T cells, the sentinels of our immune system. The team further identified substances within balsam of Peru - benzyl benzoate and benzyl cinnamate - directly responsible for stimulating the T cell response.
"Our work shows how these chemicals can activate T cells, but since we did not do a patient study, we have to be cautious about claiming that this is definitively how it works in allergic patients", de Jong says. "The study does pave the way for follow up studies to confirm the mechanism in allergic patients and design inhibitors of the response".More news: Amazon is expanding Fire TV Edition to more soundbars and automobiles
Farnesol, however, was shown to hide inside the tunnel of CD1a, displacing the resident natural lipids, making the CD1a surface visible to the T cells and resulting in an immune reaction.
Currently, there is no treatment for ACD, other than avoiding contact with the chemical causing it, although topical ointments can help sooth the rashes. In severe cases, doctors may prescribe corticosteroids. Toxic substance ivy is a regularly known trigger for unfavorably susceptible contact dermatitis, a bothersome skin rash.
The authors declare that they have no competing interests.More news: Australia wildfires from space: Satellite photos show scope of infernos