With its conclusion, the show will have aired over 100 episodes since it first debuted in 2015.
ABC Entertainment president Karey Burke added, "We couldn't be prouder of this game-changing show and the impact it has had on our cultural landscape".
The last big network show to feature an Asian-American family was Margaret Cho's "All-American Girl", which aired in 1994 and was canceled after a single season. ABC's "Fresh Off the Boat" is coming to an end after six seasons.
Inspired by chef Eddie Huang's memoir of the same name and adapted for television by Nahnatchka Khan, "Fresh Off the Boat" has become the longest-running broadcast TV sitcom about an Asian American family.More news: Italy to include climate change on school curricula
Constance Wu and Randall Park led the series as the Huang family matriarch and patriarch. "We'll miss the Huang family, and are eternally grateful for the incredibly heartfelt stories they have told these past six seasons".
So thanks to the show's declining ratings performance, combined with the possibility of losing several of its core cast members after this season, all signs seemed to be pointing toward "Fresh Off the Boat" coming to an end.
In August, the "Hustlers" star admitted to being "dramatic" and "emotional" with the rant. "So upset right now that I'm literally crying", she said. I'm emotional. But they also know that that doesn't represent me because they have a hundred episodes of behavior that proves otherwise'.
Constance has not yet commented on the series' cancellation, but her co-star Hudson David Yang has already bid it farewell.More news: The latest on Chelsea trio Mount, Barkley & Rudiger ahead of Crystal Palace
It's the end of the line for "Fresh Off the Boat".
New characters set to be introduced in a November episode of the show would be the foundation of the new series, but nothing in guaranteed. The Huang family experience particularly resonated with millions of viewers, especially those who could relate to the trials and troubles of assimilating into predominantly white, suburban pockets in America. Though the show now has a cast, it has not shot a pilot.
"I love FOTB", Wu - who portrays Jessica Huang - wrote.
Wu expressed displeasure when Fresh Off the Boat got renewed for its current sixth season.More news: England recall Bairstow as injury cover for NZ Tests