This cosmic event only happens once every 13 months, so if you miss out tonight, you'll have to wait over a year for a chance to see Jupiter up close.
See the location of Jupiter's most visible moons by using this calculator.
NASA reports that this glimpse of Jupiter's largest moons happens about once a year.More news: Rain delays Bangladesh-Sri Lanka World Cup 2019 match
As an added treat, stargazers can catch four of Jupiter's brightest moons armed with only a pair of binoculars. This will make it easier to see Jupiter's moons, which are very faint compared to the planet. Eastern time, Sky & Telescope's Bob King writes that the planet will reach ideal viewing height around 11:30 p.m. and will remain visible through sunrise, or roughly 7 a.m. During this period, the moon will form a slightly shifting lineup with Jupiter and Saturn, changing in tandem with its orbit around Earth.
U.S. space agency NASA's Juno spacecraft last week captured a stunning image of Jupiter, complete with an "intensely dark vortex" swirling across the planet's volatile surface.
But only the four brightest - Io, Europa, Ganymede and Callisto - will be visible.
Famous for its awe-inspiring stripes and swirls, Jupiter is fifth in line from the sun and the largest planet in the solar system.More news: Single-use plastics will be banned by 2021, Trudeau announces
Speaking with CNN's Amy Woodyatt and Madeline Holcombe, Robert Massey, deputy executive director of Britain's Royal Astronomical Society, offers several tips for stargazers: "Unlike stars, it won't twinkle", he says.
Don't worry if the weather is too cloudy or rainy to skywatch on Monday.
"My advice to people would be to go out and have a look because it's a handsome sight and it's really quite a thing to realize that when you are looking at the moons with a pair of binoculars - when you see them moving from one night to the next - it's worth reflecting on the fact that it was that discovery that cemented our view of the solar system as having the sun at the center", Massey said.
Juno took the iconic image during its 20th flyby of the planet on Wednesday, May 29, when the NASA spacecraft was approximately 9,200 miles from the planet.More news: "Xiaomi Mi Band 4 with 0.95" AMOLED Color Display Launched in China