The reduction is in response to financial losses the league is enduring because of the coronavirus pandemic.
The reductions will be around 25 per cent and affect employees making more than about US$75,000, according to a person familiar with the matter.
Deputy commissioner Bill Daly on Tuesday confirmed the National Hockey League has asked that players and staff extend their self-quarantine 10 days beyond the original March 27 timeline to April 6 - further pushing back the earliest team facilities can reopen.More news: HP teasing a new "no compromise" VR headset
Teams have also begun asking personnel to take pay cuts.
Bettman remains optimistic about resuming this season and awarding the Stanley Cup.
Groupe CH has established a $6-million assistance fund that will help pay employees 80 percent of their base salary for the next eight weeks, meaning the layoffs effectively translate to another 20 percent pay cut.More news: Morris County Jail Inmates To Be Released
In a statement released on the Canadiens' official website, Groupe CH said the layoffs will take effect next Monday and are necessary given the significant impact the pandemic has had on the sports and entertainment industries.
The NBA didn't immediately respond to a request for comment about whether its employees would also be asked to take pay cuts. Co-owner Josh Harris said his group had a change of heart.
"As part of an effort to do that, we asked salaried employees to temporarily reduce their wages to 20 percent while preserving all of everyone's benefits, and keeping our 1,500 hourly workers paid during the regular season. During hard times like these, our commitment to one another will help us rebound faster", Groupe CH owner, president, and CEO, Geoff Molson said in a statement. After listening to our staff and players, it's clear that was the wrong decision. This is an extraordinary time in our world - unlike any most of us have ever lived through before - and ordinary business decisions are not enough to meet the moment.More news: You can now get free access to Thor's online training plan