The ministry tweeted: "Ras al-Ayn's residential center has been taken under control through the successful operations in the east of Euphrates" River. The Syrian Kurdish-led administration said almost 200,000 people have been displaced as a result of the offensive.
At least 20 SDF fighters were killed in clashes overnight, taking their losses since the Turkish offensive began on Wednesday to 74, the Syrian Observatory for Human Rights, a Britain-based war monitor, said.
Turkish-backed Syrian opposition fighters from the Syrian National Army, are driven through the town of Akcakale, Sanliurfa province.
US troops near the northern Syrian border came under artillery fire from Turkish forces, although no injuries were reported, the US Department of Defense said Friday.
Prisoners of the Islamic State militant group (ISIS) held in Kurdish-controlled areas of north-eastern Syria are no longer the responsibility of the Syrian Democratic Forces (SDF), a spokesman for the group said.More news: Arkansas judge: Court to hear 19 adoption scheme cases
Erdogan has dismissed mounting global condemnation of the operation and said on Friday evening that Turkey "will not stop it, no matter what anyone says".
President Emmanuel Macron "reiterated the need to make the Turkish offensive stop immediately", his office said in a statement Saturday.
Germany, also a North Atlantic Treaty Organisation ally, said it was banning arms exports to Turkey and the head of the Arab League denounced the offensive.
It said one of its medical points south of Ras al-Ain was hit by Turkey on Saturday, injuring an ambulance driver and damaging the vehicle.
The statement affirmed total rejection of any Turkish attempts to impose demographic changes in Syria by using force under the pretext of creating a "buffer zone" as such an act would be a breach of global law and a war crime against humanity.More news: Priyanka Chopra Jonas on her 1st anniversary plans
Boris Johnson has told Recep Tayyip Erdoğan of his "grave concern" at Turkey's military incursion into northern Syria, Downing Street has said.
The SDF holds most of the northern Syrian territory that once made up Islamic State's "caliphate" in the country, and has been keeping thousands of fighters from the jihadist group in jail and tens of thousands of their family members in camps. By standing aside and allowing Turkey's operation to move forward, "the Americans", said one Kurdish official, "have abandoned us to a Turkish massacre".
Turkey accuses the Kurds of being terrorists and says it wants to drive them away from a "safe zone" reaching some 30km into Syria. The Army officer with knowledge of Syria said that Turkish forces previously have launched artillery over the border near US forces.
Berlin's Foreign Minister said today weaponry has been banned after Turkey launched the military attack on Wednesday, days after U.S. troops pulled back from the area.More news: Bigil Official Trailer Thalapathy Vijay, Nayanthara, A.R Rahman, Atlee, AGS
Another U.S. defense official, also speaking on condition of anonymity because of the sensitivity of the issue, said that the Pentagon "obviously" told Turkey where U.S. troops are and "they certainly go closer than we would have liked" in the incident outside Kobane.