"To safeguard our national interests, China will impose sanctions on the USA enterprises involved in the above-mentioned arms sales to Taiwan", the ministry added.
He also called it a serious violation of the "one-China" principle, under which the United States officially recognizes Beijing and not Taipei.
It bristles at any countries that might lend Taiwan diplomatic support or legitimacy.
Earlier this week, the Chinese foreign ministry said Beijing had lodged formal complaints through diplomatic channels expressing "strong dissatisfaction and resolute opposition" at the potential weapons sale, which includes battle tanks and anti-aircraft missiles. The decision follows Washington's announcement to sell $2.22 billion worth of arms to Taiwan.
As for the US, the article demanded the administration "immediately cancel the planned arms sale to Taiwan, stop selling weapons to Taiwan and terminate military contact with Taiwan".More news: Xi urged Trump to ease N. Korea sanctions - Beijing
"To safeguard our national interests, China will impose sanctions on the U.S. enterprises involved in the above-mentioned arms sales to Taiwan", Geng said.
"The 23 million people in Taiwan have the right to participate in worldwide affairs", Tsai said.
In 2010, the U.S. approved a package of Patriot missiles, Black Hawk helicopters, and other military hardware totalling $6.4 billion.
While its relations with Taiwan are technically unofficial, the United States government is required by law to assist Taiwan in its defense and is its main supplier of arms.
The Chinese government has been pushing the U.S. to cancel the planned sale and has even threatened to sanction U.S. companies involved in the deal.
"Taiwan will not give in to intimidation", she said, referring to China's efforts to suppress Taiwan.More news: Would you let an Amazon robot into your house?
And although Washington switched diplomatic recognition from Taipei to Beijing in 1979, it has remained Taiwan's most powerful unofficial ally and biggest arms supplier.
Taiwanese President Tsai Ing-wen is spending two days in the U.S. this week ahead of a trip to visit diplomatic allies in the Caribbean.
Tsai arrived in the United States on Thursday amid the objections of China and fraying relations between Beijing and the Trump administration.
Paal said the Trump Administration had yet to indicate a significant shift in the traditional US approach to Taiwan, but this could change in the event of a deterioration of USA relations with Beijing.
People engage in scuffles outside Grand Hyatt hotel, where Taiwan's President Tsai Ing-wen is supposed to stay during her visit to New York City, U.S., on July 11, 2019.
Taiwanese President Tsai Ing-wen in San Francisco in 2017. This was Tsai's first trip as president to NY.More news: Get an Amazon Echo Dot for half price — Amazing Echo bargain
Taiwan's tensions with China, with which it has developed expansive commercial ties, have grown under Tsai, who has been president since 2016.