The doctors stressed the need for proper guidelines around the new treatment, which, if proved successful in more cases, could change lives of millions of people.
Around 16 months after the London Patient received the CCR5 stem cells, doctors discontinued his antiretroviral treatments, and 18 months down the line, the man's remission persists.
When an HIV positive patient achieves viral suppression and has an undetectable viral load, not only do they have a significantly increased likelihood of improved health outcomes, but it also eliminates their likelihood of transmitting HIV.More news: Unvaccinated Oregon boy had ‘severe’ tetanus
Earlier this week, NewNowNext covered "the London patient," the second person to ever enter long-term remission from HIV after a cancer-related bone marrow transplant.
This complex treatment involves destroying a person's own immune system with high doses of chemotherapy or radiation.
These events mark an important milestone in securing domestic sustainable financing for the HIV response in Vietnam and ensuring that people living with HIV access treatment services.
The two recent cases are part of the IciStem program, which is a collaborative venture of researchers and clinicians dedicated to HIV eradication, according to a release from IciStem.More news: Eric Weddle has received offers from 11 teams
The surgical replacement of bone marrow with the stem cells of patients who have the CCR5 genetic mutation must be followed by hospitalization where patients can be monitored for and treated against tissue rejection. After receiving treatment, both patients were eventually taken off their anti-retroviral medications and subsequent examination showed that that even with very sensitive blood tests, the team could not detect HIV in their blood. This renders them resistant to most HIV infection. The patient must then be monitored to insure that his or her HIV does not come roaring back.
The patient received the bone-marrow transplant in May 2016. Though their procedures were different from those the London Patient and the Berlin Patient, this demonstrates that caution is critical when we talk about this as a "cure". HIV uses the protein to enter the cell, but it can not attach to the mutated version.
However, it's not just surviving the transplant that confers the HIV "cure" or remission.More news: Bourigeaud thunderbastard helps Rennes to victory over Arsenal
The Düsseldorf patient, who has been HIV-free for three months without antiviral medication, is in rare company as one of only three people who have successfully been cured of HIV.