The father was also home, and he was taken to the New Hanover Regional Medical Center for treatment. Officials did not know his condition as of 3:30 p.m. Friday.
Power outages have hit the Charlotte area as Tropical Storm Florence makes its way across the Carolinas.
One city in North Carolina has picked up more than 23 inches (58 centimetres) of rain in two days.
Wilmington Police Chief Ralph Evangelous agreed, telling ABC News' David Muir, "I see a biblical proportion flood event that's going to occur. I see the beach communities' being inundated with water and destruction that will be pretty, pretty epic".More news: Eliud Kipchoge smashes marathon world record by 78 seconds in Berlin
As the rough winds toppled trees and power lines Friday, power was knocked out to more than 600,000 North Carolina customers.
Storm surges, punishing winds and rain are turning some towns into rushing rivers - and the storm is expected to crawl over parts of the Carolinas into the weekend, pounding some of the same areas over and over. If confirmed by the National Weather Service, that would break the state record for rainfall from a tropical cyclone.
More than 60 people, including many children, were evacuated from a hotel in Jacksonville, North Carolina, after strong winds collapsed part of the roof. The couple died in a house fire in Cumberland County, N.C. on Friday.
Due to downed trees, emergency crews were unable to get to the woman before she passed away.
Peggy Perry, who was rescued by another group in New Bern, said rising water forced her into the upper level of her home. Volunteers are using private boats to pitch in and help, city spokeswoman Colleen Roberts said.More news: Jabari Bird steps aside amid domestic violence charges
By Friday morning, the shore was flooded, and buildings were damaged, in video she put up on Facebook. "Everything around us is underwater".
Jeff Byard, associate administrator for response and recovery at the Federal Emergency Management Agency, said "24 to 36 hours remain for significant threats" from heavy rain, storm surge and flooding.
Florence arrived at the Carolina coast as a Category 1 storm, its 90-mph winds far slower than the fearsome 150 miles per hour of just a few days ago. Six sheriff's officers came to his house to rescue him Friday morning, but he didn't need to leave since the water was dropping by then.
Forecasters warned that drenching rains of anywhere from 1 to 3½ feet as the storm crawls westward across North and SC could trigger epic flooding well inland over the next few days. Rainfall of up to 20 to 40 inches could fall over the next five days in some areas, forecasters say.
Governor Cooper said the hurricane was likely to "continue its violent grind across the state for days".More news: Ian Wright's ideal response after Alan Shearer claims Arsenal aren't that good