A mere week after health officials declared the end of Democratic Republic of Congo's ninth Ebola outbreak since 1976, a "cluster of presumptive Ebola cases" have surfaced in the country, according to the World Health Organization.
Twenty deaths from hemorrhagic fever have also been recorded in the area, the ministry said.
Congo declared the outbreak on Wednesday, just days after another that killed 33 people in the northwest was declared over.
Four people have tested positive for Ebola in and around Mangina, a town of about 60,000 people in North Kivu province, 100 km (62 miles) from the Ugandan border.More news: Death toll rises to 52 in Saudi-led airstrikes on Yemen's Hodeidah
The virus was discovered in a village near the city of Beni in North Kivu, which hosts more than one million displaced people.
"Although we did not expect to face a tenth epidemic so early, the detection of the virus is an indicator of the proper functioning of the surveillance system", said the country's health minister, Oly Ilunga Kalenga, in a statement. "This new cluster is occurring in an environment which is very different from where we were operating in the northwest", said Dr Peter Salama, WHO Deputy Director-General, Emergency Preparedness and Response.
"Since we are coming out of another Ebola outbreak, we have kept staff and equipment in place", said Dr Matshidiso Moeti, WHO Regional Director for Africa.
This outbreak is more than 1,500 miles from the earlier one on the opposite side of the country.More news: India pinning hopes on Kohli to win gripping test vs England
Ebola is believed to be spread over long distances by bats and can turn up in bush meat sold at food markets throughout Congo.
Transmission among humans then typically spreads through close contact with the blood, body fluids, secretions or organs of someone who is sick with Ebola or has recently died.
An outbreak from 2014 to 2016 killed over 11,000 people in Sierra Leone, Liberia and Guinea.
Congolese and global health officials deployed an experimental vaccine that helped contain its spread after it reached a large rivr port city. Ebola is a constant threat in the Democratic Republic of Congo as the virus thrives in heavily forested areas.More news: Google Maps' new feature can help others 'track' your smartphone's battery