On Sunday night, Israeli warplanes attacked the al-Nayrab air base near the Syrian city of Aleppo.
Late Sunday, state news agency SANA said Israeli missiles had hit near a strategic air base, but said there were no casualties.
An Israeli military spokesman declined to comment on the report.More news: Prince Harry and Meghan visit Nelson Mandela tribute in London
The Syrian Observatory for Human Rights said the attack, which it too said was likely carried out by Israel, targeted a Syrian regime site.
Israel has struck locations in Syria many times in the course of the foreign-backed conflict, targeting both military bases and residential areas.More news: UK's May faces fresh revolt over Brexit trade bill vote
The raid came hours before a major summit between Russian President Vladimir Putin and US President Donald Trump, where Syria and Iran are expected to be on the agenda. Israeli Defense Minister Avigdor Lieberman on Monday told media outlet Ynet that he had no knowledge of the incident but said Israel's policy toward Iran in Syria had not changed.
However, he stressed that Israel's policy toward Iranian forces in Syria hasn't changed.
Iran is a key ally of Syrian regime leader Bashar al Assad and backs a number of militias, including Lebanon's Hezbollah, fighting in support of Assad. Israel downed the drone a day earlier with a patriot missile.More news: Kawhi Leonard Holdout Would Cost Him His Free Agency
The Syrian government has on multiple occasions slammed Israeli aggressive actions and also warned about the "dangerous repercussions" of Israeli assaults on its territories.