Foreign Minister Sergey Lavrov said Moscow sees Thursday's strikes as a "very alarming development".
Israeli Prime Minister Benjamin Netanyahu made a televised address lauding Trump's Iran policy and alluding to the tensions over Syria. Netanyahu visited Moscow Wednesday to attend celebrations marking the WWII victory anniversary.
French President Emmanuel Macron called for a de-escalation of tensions in the Middle East on Thursday after Israel said Iran had launched an overnight rocket strike from Syria on an Israeli military base and that it had responded with its own missiles.
Israeli officials have been predicting an Iranian "attack" against them in retaliation for the various Israeli strikes in recent weeks.
The United Nations, Russia, France, Germany and Britain have urged Israel and Iran to avoid any further escalation after Israel carried out air raids against what it said were Iranian targets in Syria.
Iran Does Not Want 'New Tensions' in Mideast, Says Rouhani
Al-Ikhbariya TV said Israel also targeted military posts in southern Suweida province, including an air base, and struck near Homs in central Syria. The two countries were the main allies of the United States in the region, and Iranian oil was shipped to Israel during the 1973 war. An airstrike on a military base in Syria last month, which Iran and Russian Federation blamed on Israel, killed seven Iranians. Le Maire asked. "Or do we want to say we have our economic interests, we consider we will continue to do trade with Iran?".
But the chairman of Iran's parliamentary committee on foreign affairs condemned Israel for carrying out the strikes in Syria.
Israel's military says it managed to intercept most of the projectiles, adding there was minimal damage and no casualties.
According to Conricus, the rockets were targeted at front-line Israeli military positions in the Golan Heights. In 1974, Israel and Syria reached a cease-fire and a disengagement deal that froze the conflict lines with the plateau in Israeli hands.
Both Russia and Iran have intervened in war-torn Syria in support of President Bashar al-Assad.More news: House Speaker Paul Ryan moves to stop Republican revolt on immigration
British Foreign Secretary Boris Johnson said Iran must refrain from "further actions that will only lead to increased instability", and called on Russian Federation to press the Syrian government to work for a broader political statement.
The head of the Observatory, Rami Abdurrahman, said five Syrian soldiers, including two officers, and 18 militia fighters were killed. Iran's strategic intent is clear.
The UK-based Observatory said the missile strikes hit depots and rocket launchers, killing 15 individuals including eight Iranians.
He appeared to be referring to conflicting messages from the White House on how long it plans to keep American troops in Syria and its plans going forward.
Another possible group, Tamimi said, was a Palestinian organization linked to Hezbollah and the IRGC, such as the "Force of Return", which is now fighting for the regime of Bashar Assad in the Yarmouk camp outside Damascus.More news: Mets' Cespedes sidelined with hip strain
Iran on Friday supported Syria's right to defended itself against Israel's aggression, state TV reported, accusing the worldwide community of remaining silent over Israel's attacks on Tehran's key regional ally.
"They must remember that if it rains here [in Israel], it will pour there", he said.
In the most direct confrontation between Israel and Iran to date, the two regional enemies exchanged fire for hours during a volatile night in the Golan Heights.
Israel says the targets included weapons storage facilities, logistics centers, intelligence sites and logistic sites used by elite Iranian forces in Syria.
"Air defenses confronted tens of Israeli rockets and some of them reached their target and destroyed one of the radar sites", Syrian state news agency SANA reported, citing a military source. Israel has tried to stay on the sidelines but has acknowledged over 100 airstrikes over the past seven years.More news: Intel's self-driving cars testing in Jerusalem