Addressing her Bafta nomination, she said: "I am so proud of the show and I'm so proud of everyone's work on it, and it just feels unbelievable when you do something and people enjoy it and watch it anyway and then to come to something like this, it's lovely".
The newcomer beat the likes of The Crown's Claire Foy, Little Boy Blue's Sinead Keenan and Line of Duty's Thandie Newton. Sean Bean won Best Drama Actor for playing a troubled priest toiling in Liverpool in the fictional series "Broken" while Brian.
Several winners dedicated their prizes to real-life people they portrayed.
The cast of Three Girls praised the social workers and police officers who risked their jobs, while accepting their award for the drama, which told the real story of abused and sexually exploited school girls from Rochdale.More news: Missing Oregon child abandoned by father found naked, alone in forest
The single drama award went to the crime drama "Murdered for Being Different" over "Against the Law", an episode of "Black Mirror" (Hang the DJ) and the TV version of the Olivier-winning comedy "King Charles III".
It was not a successful night for diverse nominees.
Other winners included The Handmaid's Tale winning the award for best global series, This Country winning Scripted Comedy, Daisy May Cooper winning Female Performance in a Comedy Program for This Country and Toby Jones winning Male Performance in a Comedy Program for Detectorists, among others.
The Handmaid's Tale was the victor in the category of worldwide series.More news: UFC's Tim Kennedy Waterboards Himself to Prove 'It's Not Torture'
BBC Three comedy This Country picked up two gongs at the ceremony, with star Daisy May Cooper landing the female performance in a comedy programme prize, while the show won the scripted comedy award.
Nolan is not the first of the gaming industry to receive a BAFTA Special Award. Amazon Prime was snubbed completely from the awards.
Earlier, as guests were arriving, police were called when a man in his 20s was stabbed outside the National Theatre on the Southbank, London several hours before the Baftas began at the Royal Festival Hall nearby.More news: Mosque attack 'wreaks havoc' on religiously tolerant South Africa, bishops say