While he didn't win 17-year-old Sessegnon became the first player from outside the English top flight to be nominated for the award.
Bristol City's Lauren Hemp was named Women's Young Player of the Year.More news: Celgene Corporation (CELG) Analysts See $1.77 EPS as of May, 4
Salah attended the PFA Awards alongside Liverpool skipper Jordan Henderson.
Salah's manager Jurgen Klopp sent the Egyptian a classy message after he was handed the award over video link.
He's breaking record after record, and has already weighed in with 31 (!) league goals.More news: Naxals killed in ongoing encounter in Maharashtra's Gadchiroli
While Salah's form this season has caught many off-guard, there was little surprise in the PFA's eventual announcement after a photo was leaked earlier in the evening showing the former Chelsea and Fiorentina star holding the trophy.
Salah scored his 31st league goal in Liverpool's 2-2 draw against West Bromwich Albion on Saturday, equalling Luis Suarez, Cristiano Ronaldo and Alan Shearer for the most Premier League goals scored in a 38-game season. I am sorry, maybe with numbers, there are numbers guys better than him, but no player in this season with the team who wins [the title] five games before the end, and he was the best. "But at the end in summer time we will be at home being champions and for that to happen the players have to play".
Coming a distant second was De Bruyne, who took 14% of the votes.More news: Syrian Army Attacks Terrorist Groups in Southern Damascus
When asked if he had a point to prove, he added: 'I think I left, and then I came back as a different person, a different man, a different player.