Manchester United (-475) had some starters nicked-up during the recent worldwide break, but it has won its last four home matchups, while Swansea City (+1300, draw +500) has generated little offense on the road all season.
"I will not complain", he said.
"What's happened in the last week is so unfair. That disappoints us the most", Pochettino told Sky Sports. I will be so happy and I will celebrate but I think United will win. "I am excited to be champions with our fans".
All of Liverpool's prolific front three were on target as Sadio Mane and Roberto Firmino struck either side of Salah's deft header to take their combined tally for the season to 82.More news: Oladipo, Pacers Hand LeBron, Cavaliers Game 1 Playoff Defeat
Jesus nearly got the third goal but he blasted it in the 63rd minute, both managers made their first changes as Nicolas Otamendi replaced Sane and for Tottenham, Heug min Son was brought in for Erik Lamela.
Things went from bad to worse for Spurs and their captain as Lloris' reckless lunge on Sterling - which appeared outside of the area - handed City a penalty which Gundogan coolly slotted home. The referee pointed to the spot, however, and Gundogan rolled home the kick.
But, they couldn't keep the clean sheet for long as Christian Eriksen finds the back of the net in the 42ndd minute after benefiting from a poor defensive play by Aymeric Laporte as his weak attempt to clear the ball puts his side under pressure.
"I said after 10-15 minutes we will be champions", said Guardiola of his side's fast start.
As usual, City controlled the possession of the game as they claim 71% of the possession as early as the sixth minute - just like they had done in their defeats to Manchester United and Liverpool barely a week ago.More news: 'Rampage' Stomps Past 'A Quiet Place' for $34.5 Million Box Office Win
Club-record signing Coutinho then delivered an outswinging corner from which Samuel Umtiti headed in Barca's second in the 51st minute, shortly after Gerard Pique had saved Umtiti's blushes by clearing a shot from Valencia forward Santi Mina off the line following a slip by the France defender.
Pochettino's men were uncharacteristically poor in the first 45 minutes as both Eric Dier and Mousa Dembele were left overrun in midfield.
The Barca coach praised his players for putting the Roma defeat behind them.
It was a move more likely to have been made by Jose Mourinho, not Guardiola, but after those painful defeats against Liverpool and United - and the manner by which they occurred - the City manager chose to deploy the handbrake and it was the right move at the right time. "It was more important that we picked ourselves up after a hard week", Valverde said.More news: Tornado Watch For Most Of The Area