The 25-year-old appeared crushed by the defeat and snapped sarcastically at reporters when asked where he would go from there. "I count my millions", said the former Wimbledon quarter-finalist, who reached the third round at Melbourne Park previous year.
BC-TEN-Australian Open-Tomic Out, 331 Tomic's troubles continue, misses a spot at Australian OpenBernard Tomic's troubles have continued into 2018 with a loss in the last round of qualifying for the Australian Open.
"You go do what I did. Good luck guys. Bye bye".More news: Housley says more than $150K raised for Senate race
Tomic is at a career crossroads.
But Tomic's final singles outing at Melbourne Park began as a no-contest.
Moving poorly and with no intensity, Tomic simply gave away points on Sonego's serve deemed out of reach.
Out of nowhere, he lifted in the second set, maximising his effort in his own service games to push through.More news: Sanchez To Manchester United A 'Done Deal'
Mousley, 22, will have to a wait a little longer to make his debut at a grand slam after falling in 70 minutes to Spaniard Jaime Munar 7-5 6-2.
The crowd lifted with the Queenslander and he responded in the second-set tiebreak, fist-pumping his way back to the chair as he levelled the match.
A former world number 17 but now ranked 142, Tomic will miss out on his home grand slam after 10 successive main draw appearances.
Tomic was criticised for ruling himself out of the Rio 2016 Olympics because of an "extremely busy" schedule, a year after he was dropped by Tennis Australia - for a second time - from their Davis Cup squad.More news: OR secures victory against Arizona by 18 - Recap, Box score
Whether he will return to the tour in a full-time capacity is yet to be made clear.