In a blow to May's authority, Justine Greening quit the government after refusing to take up a position at the helm of the Department for Work and Pensions and Jeremy Hunt persuaded the prime minister he should remain in a beefed-up role as secretary for health and social care - a decision that the Guardian understands scuppered Downing Street's original plan to appoint Greg Clark as the new health secretary. She was appointed as deputy whip two months ago, and has now joined the cabinet for the first time as Secretary of State for Work and Pensions, a department in which she was a junior minister under David Cameron.
All eyes will be on movement at the top-end of Cabinet but Prime Minister May wants to use this latest reshuffle to promote new talent to the lower levels of government, according to numerous reports.
Chris Grayling, the transport secretary, has also been floated as a potential successor to Green.
The new education secretary, Damian Hinds, attended a grammar school.
The former housing minister briefly served as immigration minister before taking on the job of rebuilding the Tories' campaigning strength for the next general election.
There was some tinkering: David Lidington was moved from the justice beat - where he had worked for just seven months - to take on Damian Green's old role as Cabinet Office minister.More news: Sino-global Shipping America LTD (NASDAQ:SINO) Sentiment Worsens in 2017 Q3
Esther McVey becomes Work and Pensions Secretary.
A former digital minister, Matt Hancock has been promoted to Secretary of State for Digital, Culture, Media and Sport.
Ex-culture secretary Karen Bradley was moved to the politically sensitive Northern Ireland role vacated by Mr Brokenshire.
Hunt's title has been tweaked to Secretary of State For Health and Social Care. He has been a minister at DCMS.
Four of the 10 women attending meetings are not full members of cabinet, which means May's leading team has a gender pay gap with men earning on average £138,688, 11% more than the women at £124,758.
Shailesh Vara returns to the Government after a spell on the backbenches as parliamentary under secretary in the Northern Ireland Office.More news: GPS Fusion Founder Glenn Simpson: FBI Had Source Inside Trump Organization
There is real anger too among some members of the government at how Justine Greening was treated on Monday night, compared to her male colleagues.
It's a key role both for Brexit and the stability of May's minority government as it will involve delicate negotiations over the Irish border and devolved government with the Democratic Unionist Party, whose lawmakers prop up the government after May lost her majority in June's vote.
Africa minister and former diplomat Rory Stewart has gone to the Ministry of Justice - a shift which was criticised by Tory grandee Sir Nicholas Soames who questioned why a "really knowledgeable" foreign policy expert was being moved to a domestic role.
And Chief Secretary to the Treasury Liz Truss also stays in post.
Environment Secretary Michael Gove, International Development Secretary Penny Mordaunt and International Trade Secretary Liam Fox all remain in the same jobs. The appointment of Caroline Nokes as Immigration Minister attending Cabinet is also freaky.
"Today's headlines are what they are - tomorrow and onwards we will be getting the really important stuff which is about what we are doing, what we are delivering in government".More news: Jay Rock, Kendrick Lamar, Future, James Blake Debut 'King's Dead'
Baroness Evans stays as Leader of the House of Lords.