Liverpool have managed to take an inconsistent start and turn it into a very strong season as they are now battling near to the top of the league. But, City have just enough to clinch all three points from Anfield, and The Hard Tackle expects a 2-1 win for Guardiola's side.
Manchester City midfielder İlkay Gündoğan has revealed why he chose to join the club instead of reuniting with Jürgen Klopp at Liverpool - who managed the German global during his time at Bundesliga side Borussia Dortmund. City hasn't made any moves yet, but the rumor is that they're closing in on Arsenal's Alexis Sanchez and could have him by the weekend.
But Liverpool have been here before when they were forced to accede to Luis Suarez's requests to move to the Catalan giants.
"The players have two choices: Follow what you (the media) say, or follow me".
"It is a good test for us".
Virgil van Dijk made a dream debut after scoring a late victor against the Toffees and the Dutch worldwide is fully expected to keep his place this weekend. Most experts scratched their heads at the time, but City proved everyone wrong with a vengeance. Liverpool are boosted by the return of Mohamed Salah, who suffered a groin problem. Even in midweek, when City looked lackluster against Bristol City, they still managed to produce a late victor.More news: Jose Mourinho gives injury update of Zlatan Ibrahimovic
It's this approach which Klopp will need his men to get right from the first whistle at Anfield, retaining and turning the ball over in order to deny City's ruthless midfield the chance to fall into their creative stride.
Ahead of the crunch showdown Sportsmail assesses the nuances of the two sides and where this clash of the titans could be won and lost. After 22 games they have conceded 25 times, the most of any top six team bar Arsenal.
The Hammers rode their luck at Shrewsbury to remain in the FA Cup although a replay next week would not be what new manager David Moyes wanted.
Carlos Carvalhal is without the suspended Kyle Naughton for Swansea's trip to St James' Park but Leroy Fer's appeal against a red card was successful.
It is partly due to their record at Anfield: four straight defeats, no wins in 14. The last time they managed a win was in 2003, so that's another unbeaten record Liverpool want to protect.More news: Nintendo got to show off Dark Souls: Remastered first for a reason
A hostile reception is likely to lie in wait once more for the England global, who has made tremendous strides under Guardiola and scored 18 goals in 29 matches this season.
"Pep told me to play with freedom like [Lionel] Messi, not like Messi - it's impossible!" But you know my answer.
Two more clubs given a lift by FA Cup victories but while Brighton would never sniff at a win over bitter rivals Crystal Palace, the Baggies needed it more, ending a run of 21 games without a win at Exeter.
Despite a height disparity of about ten inches between the two men, Aguero has honed his trade in slipping the last man with his unplayable movement and reading of the game.
"Last time was 15 years ago". Bournemouth are the great entertainers, their last seven games featuring 28 goals. The Portuguese said earlier: "If - next summer - we are going to sign a midfielder player, it's to replace Michael Carrick".
United, however, will face opposition from City's Pep Guardiola who is also on the lookout for a quality defensive midfielder. Even Jose seemed to enjoy it.More news: Stocks to Lookout For: Huntsman Corporation (HUN), Teva Pharmaceutical Industries Limited (TEVA)