A group of 14 young men took the maximum daily dose of the drug ibuprofen for several weeks, and researchers compared their hormone levels with a second group given a placebo. The condition occurs when the body has to boost levels of testosterone because normal production in the testes has fallen.
There are new concerns that men who take a lot of Ibuprofen could face fertility problems.
The scientists say their findings are significant because ibuprofen is among the most commonly used medicines worldwide, available without a prescription and used by the general population as well as elite athletes.
The detrimental effects of daily ibuprofen were almost immediate. Luteinizing hormone or LH, is secreted by the pituitary gland and it is the key hormone that stimulates the testes to produce the male hormone testosterone.More news: Switzerland bans boiling live lobsters in animal welfare reform
In March of previous year Jiri Dvorak, Fifa's former chief medical officer, warned of an "alarming trend" among elite football players to "abuse" legal painkillers such as ibuprofen.
Jiri Dvorak, the former chief medical officer of FIFA, warned in March 2017 of an alarming trend of painkiller use, notably Ibuprofen, among football players, as the drug does affect doping tests, The Guardian reported. This eventually lead to infertility or "hypogonadism" and other associated conditions such as increased risk of heart disease, stroke, heart failure and depression.
Dr Kevin McEleny, from the British Fertility Society, said: "Some studies have shown that exposure to drugs such as ibuprofen can affect testicular health in the foetus".
Within 14 days, testosterone-producing hormones in the men taking ibuprofen dropped, causing compensated hypogonadism, according to USA Today . Also, given the results come from such a small sample, more research is definitely needed. The highlighted cardiac and hormonal disruption risks point toward the need to be cautious with such medications, and anyone who is concerned should talk to their doctor about it before taking the medication.More news: Nissan's auto of the future can read your brain
According to Bernard Jégou, co-author and director of the Institute of Research in Environmental and Occupational Health in France, the new study is a continuation of research that began with pregnant women.
He added: 'Hitherto, most warnings regarding this family of painkillers have focused on limiting long term use in the elderly to prevent gastrointestinal, renal and cardiac adverse effects.More news: Gov. Pete Ricketts: 'Nebraska Is a Pro-Life State'