Inter Milan have been linked to Mkhitaryan, with Jose Mourinho appeared to hint that a January exit was possible, and Portuguese midfielder Joao Mario is reported to be a possible part of the deal which could happen next month.
If he continues to play such a peripheral role, United would surely consider offers for a player who cost up to £30million 18 months ago. "That's my approach as a manager".
Both Henrikh Mkhitaryan and Luke Shaw have struggled to get first-team minutes, fueling speculation of moves away.
I think every player has a price.More news: Interstellar visitor stays silent: No signs of life yet on 'Oumuamua
While teething problems in Premier League football were to be expected, his sub-standard performances this season have been startling - and Mourinho has acted accordingly, leaving him out of seven of his last eight matchday squads.
"I had [Ander] Herrera as a midfield player, Zlatan [Ibrahimovic] as a striker and Marcus [Rashford] as a second striker and winger".
But BBC Sport understands there has been a "breakdown of trust". "Especially players who belong to other clubs".
Mourinho said he was confident with his options at the back, however, and that United would be able to cope in his absence.More news: Monique S. Matheson Sells 10000 Shares of Nike Inc (NKE) Stock
"I signed a three-year contract here because it was the time myself and the board we decided on at that time". Ashley Young has impressed there, but Daley Blind and Matteo Darmian haven't done enough to stake their claim in that position.
"I don't like the January market just to buy".
However, according to ESPN FC, Mkhitaryan's absence is down to a row with Mourinho, which took place during a video analysis session at the club's training ground last month.
Mourinho recently claimed that the decision to omit the Armenian global was due to the fact that he had players more deserving of a position on current form.More news: Puma Biotechnology (PBYI) Earns Daily Coverage Optimism Rating of 0.19